Blueprint Medicines is committed to supporting investigator-sponsored research (ISR) that contributes to the scientific and medical understanding of our products and relevant disease areas, and which enhances the practice of medicine, ultimately improving patient care.
ISR includes both clinical and non-clinical studies designed and managed by an independent investigator outside of Blueprint Medicines. The investigator and their organization assume responsibility for the management and conduct of the study through the duration of their research. We welcome well-written, scientifically sound research proposals that align with our areas of medical and scientific interest (see below) and meet a multitude of goals, including addressing unmet medical needs, addressing gaps in existing scientific understanding, improving patient care or sparking new ideas for disease-related research.
Support for an approved ISR may come in various forms including funding, product and/or material, or in some cases, both funding and product in response to unsolicited ISR requests, as allowed under local laws and regulations. All requests will be critically reviewed, and a decision will be made based on scientific merit, feasibility, and our current research objectives and available resources. Proposals that directly compete with our current and/or future studies will not be considered.
How to submit an ISR request
Brief requests for ISR support (ISR Concept) must be submitted via our web-based portal. The ISR Concept will be reviewed by Blueprint Medicines’ Scientific Review Committee (SRC). If the SRC approves the ISR Concept according to the criteria described above, the investigator will be invited to submit a more detailed proposal containing the following, at a minimum:
- A comprehensive description of the proposed ISR study, including the nature and scope of the support requested;
- A curriculum vitae (CV) or resume that documents previous clinical research experience of the proposed investigator(s) and other key research staff;
- Evidence of good medical standing, including no restrictions by a regulatory authority (debarment) to undertake clinical research, if applicable;
- Detailed project budget, including itemization of costs and services;
- Proposed research timelines and milestones, including a description of anticipated publications and/or presentations; and
- Any additional relevant supporting documentation required by Blueprint Medicines’ Scientific Review Committee.
Last updated on [March 15, 2022].